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However, the small sample-size, the short treatment period, the absence of control groups, the lack of liver biopsy evaluation after treatment are just some of the limitations of these studies

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Additionally, betaine supplementation can increase the levels of fibroblast growth factor 21 (FGF21) in the liver and circulation, enhance white fat oxidation capacity and whole-body energy expenditure, thereby enhancing blood glucose homeostasis and metabolic health (79, 83, 85)

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